GLP-3 Triple — In Vitro Research Overview

GLP-3 Triple is a modified research peptide analog used by researchers studying GLP-1 and GIP receptor binding kinetics and downstream metabolic signaling in cell culture.

Chemical Identity

In Vitro Research Context

GLP-3 Triple (CAS 2611742-08-0) is a research-grade peptide analog incorporating modifications at residues 2 and 20 to extend in vitro stability. Researchers use this compound in receptor-binding assays examining dual GLP-1 and GIP receptor affinity, ligand-induced internalization, and cAMP signaling cascades in relevant cell lines. It is a batch-verified research compound supplied strictly for in vitro laboratory use.

Metabolic researchers studying incretin biology and beta-cell signaling models have employed GLP-1/GIP dual-agonist research peptides to characterize receptor pharmacology in cell-based assays. Independent HPLC-UV purity testing and LC-MS sequence confirmation are provided with every batch. This research peptide is supplied for Research Use Only (RUO) — not for human or veterinary use.

Research Applications

The following in vitro laboratory research applications have been reported in published literature. All listed uses are strictly in vitro — this research compound is not for in vivo, human, or veterinary use.

• GLP-1 and GIP receptor binding assays (competitive binding, Kd determination)
• cAMP signaling pathway studies in pancreatic beta-cell lines
• Ligand-induced receptor internalization models
• Incretin biology in vitro research
• Metabolic signaling cascade studies
• Comparative dose-response studies against native GLP-1 and GIP peptides

Laboratory Notes

Lyophilized powder maintains stability at −20°C for 24 months in sealed original packaging. Avoid exposure to repeated freeze-thaw cycles to preserve sequence integrity.

Batch Verification

Every batch of this research compound is independently tested by Freedom Diagnostics, an ISO 17025 accredited independent analytical laboratory. Testing includes:

• HPLC-UV purity determination (reported as % area)
• LC-MS sequence and molecular weight confirmation
• Net content (mg) gravimetric verification
• Full Certificate of Analysis (COA) with batch number, accession number, and laboratory stamp

The COA batch number is printed on every vial and scannable via QR code for direct verification. Researchers can cross-reference the accession number against the Freedom Diagnostics laboratory record independently.

External Research References

The following resources provide background context for researchers studying this compound:

• GLP-1 receptor biology
• GIP receptor background
• In vitro research methodology
• HPLC purity testing
• ISO 17025 accreditation standard